Raw Antihistamine Reset Protocol for Dogs

Reset Duration
The reset lasts for 21 to 30 days. During this time, proteins are not rotated, and dietary variety is intentionally restricted. Consistency is therapeutic and allows the histamine system to stabilize.

Core Principles
Freshness is prioritized over novelty. Only unaged red meats are used, with minimal ingredients and immediate freezing after processing. Thawing is limited to a maximum of twenty-four hours. This approach is not low-protein, vegetarian, or avoidance-based. It is a supportive elimination strategy designed to restore enzymatic capacity.

Protein Selection
One protein source is selected and used exclusively. Preferred options include beef, lamb, bison, goat, or fresh, non-aged venison. Poultry, pork, fish, and rabbit are avoided during the reset due to their higher likelihood of histamine reactivity. Red meats provide heme iron, zinc, vitamin B12, copper, and methionine, all of which are required for proper histamine metabolism.

Diet Composition
The daily diet consists of approximately eighty percent muscle meat, preferably from whole cuts. Ten percent of the diet comes from organs, with liver limited to three to five percent and the remainder supplied by the kidney or spleen. The final ten percent is provided by raw meaty bones or a clean calcium source when bone is not tolerated. Organs are essential for copper-dependent DAO activity, B-vitamin-driven methylation, and vitamin A-mediated mast-cell regulation.

Fat Guidelines
Natural ruminant fat from beef or lamb is encouraged, with small amounts of fresh tallow added only if additional calories are needed. Poultry fat, fish oil, seed oils, and oxidized or reheated fats are excluded, as unstable fats worsen histamine responses.

Feeding and Handling
Food handling is critical to success. Meat should be frozen immediately after portioning, thawed only once, and fed within twenty-four hours. Slow thawing at room temperature, feeding leftovers, or leaving bowls uncleaned promotes histamine formation. Histamine develops before cooking and freezing, making handling more important than ingredient choice.

Items Removed During the Reset
All kibble, canned, dehydrated, or baked foods are eliminated, along with bone broth, fermented foods, probiotics unless verified as non-histamine producing, apple cider vinegar, turmeric blends, green powders, superfood mixes, and all treats. Even natural additions can perpetuate mast-cell activation.

Supplement Use
Supplementation is optional and should be strategic. Magnesium may support calming and mast-cell stability, zinc may be considered if deficiency is suspected, and vitamin B6 can assist DAO activity. New supplements should generally be avoided during the first week to ten days unless medically required.

Expected Improvements
During the first week, many dogs show reduced frantic itching, improved stool consistency, and less ear heat or redness. By the second week, skin normalization, reduced post-meal reactivity, and improved sleep are common. Weeks three to four often bring fewer flares, a wider tolerance window, and more stable digestion. Healing is not linear, and mild early flares can occur as histamine load decreases.

Common Pitfalls
Results are often undermined by rotating proteins prematurely, adding probiotics too early, using aged meat, overfeeding liver, adding vegetables or fiber, or abandoning the protocol before stabilization occurs. The goal is systemic calm before expansion.

Transitioning Off the Reset
After twenty-one to thirty days, and only once the dog is stable, new foods may be introduced one at a time with five to seven days between additions. Red meat should remain the foundational protein. Many dogs labeled histamine intolerant react only when dietary demands exceed their enzymatic capacity.

The Grounding Truth
Histamine issues in dogs are rarely caused by raw food itself. They arise from aged proteins, oxidative stress, and diets that overwhelm histamine-processing enzymes.